What better place than Italy to enjoy unique wellness experiences? The best spa hotels in Italy combine Italian hospitality, breathtaking landscapes, and cutting-edge treatments, creating wellness destinations that captivate guests from all over the world. In this guide, you’ll discover the excellence of Italian wellness: from Alpine resorts in Trentino-Alto Adige to historic spas in Tuscany, from luxury hotels in the Dolomites to serene lakeside retreats. Hotel Bigio with QC Terme San Pellegrino is part of this panorama of excellence, offering authentic Lombard wellness in the Liberty-style setting of Val Brembana.
Northern Italy: Mountains and Lakes of Wellness
Alto Adige – Alpine Excellence
The Quellenhof Luxury Resort in Val Passiria represents the pinnacle of Alpine wellness with its 10,550 sqm spa, 23 different saunas, and 12 pools, including a heated infinity pool with panoramic mountain views. For over 11 years, it has consistently ranked among the top 10 spas in Italy.
The Gardena Grödnerhof Hotel & Spa in Ortisei perfectly blends timeless elegance with the surrounding nature. Treatments harness the healing properties of Alpine herbs in a refined setting that reflects Alpine tradition.
Trentino – Wellness Among the Dolomites
Rosapetra Spa Resort in Cortina d’Ampezzo is featured in the 2025 Luxury Spas guide by Condé Nast Johansens. Here, luxury meets nature in sublime harmony, with treatments that highlight the beauty of the UNESCO Dolomites.
Vigilius Mountain Resort offers a fully sustainable approach to wellness, with eco-friendly interiors and a restaurant serving only local ingredients. The wellness center features personal training, trekking, meditation, and Nordic walking.
Lombardy – Lakes and Traditional Spas
Lake Garda – The Temple of Wellness
Lefay Resort & SPA Lago di Garda in Gargnano won the 2016 World SPA & Wellness Awards for “Best SPA Destination in the World.” Its 3,800 sqm spa includes panoramic pools, saunas, outdoor wellness paths, and a team of holistic experts.
Hotel Bigio and QC Terme San Pellegrino represent wellness excellence in Val Brembana. The Belle Époque thermal baths, set in the Liberty-style architecture of the village, offer panoramic pools, saunas with views, and unique wellness paths. The hotel complements the experience with family hospitality and traditional Bergamasque cuisine.
Milan – Urban Wellness Oases
Four Seasons Hotel Milano houses an underground spa restored by Patricia Urquiola, offering grape-based treatments in spaces that blend modern elegance with monastic history.
Central Italy – Historic Spas and Iconic Landscapes
Tuscany – Luxury Among Hills and Thermal Springs
Castello di Casole in Val d’Orcia combines a 13th-century estate with one of Italy’s most luxurious resorts. The spa harnesses the beneficial properties of Tuscan thermal waters in a setting of rare beauty.
Il Pellicano in Porto Ercole, on Monte Argentario, is a haven of pure beauty, with treatments using products from the historic Florentine house Santa Maria Novella.
Emilia-Romagna – Spa Tradition
Terme di Castrocaro with the Lucia Magnani Health Clinic merges science and wellness, combining holistic treatments with cutting-edge technology for true rejuvenation.
Southern Italy – Sea and Mediterranean Wellness
Sicily – Exclusive Wellness Destinations
ADLER Spa Resort SICILIA near Agrigento exemplifies sustainable luxury designed in harmony with nature. Rooms with private gardens and sea views offer a sanctuary of tranquility, while the spa includes four pools with breathtaking Mediterranean views.
Verdura Resort, part of the Rocco Forte Hotels chain, spans 4,000 sqm in the Sicilian countryside, offering exclusive rituals and treatments that celebrate Mediterranean traditions.
Puglia – Salento Wellness
Borgo Egnazia represents the pinnacle of wellness in Puglia, with its spa reinterpreting Mediterranean wellness rituals using local products and traditional techniques.
The Italian Excellence in Wellness
Italy’s best spa hotels represent a unique heritage of natural beauty, thermal history, and wellness innovation. Each region offers distinctive experiences reflecting the local territory and traditions.
Hotel Bigio with QC Terme San Pellegrino perfectly embodies this Italian excellence: Belle Époque thermal history, Liberty-style architecture, modern treatments in panoramic pools, and warm Lombard hospitality.
Discover why Italy is considered one of the world’s most desirable wellness destinations: here, every spa stay becomes an experience that nurtures body, mind, and soul amid unmatched landscapes.
Experience the excellence of Italy’s best spa hotels with QC Terme San Pellegrino and Hotel Bigio in San Pellegrino Terme.
